Effective Suzuki-Miyaura Arylation and Sonogashira Aryl Alkynylation on N-Heteroaromatic Cations: Synthesis of Substituted Pyridine-Fused Cationic Heterocycles

摘要

Suzuki-Miyaura and Sonogashira cross-coupling reactions were efficiently employed for the syntheses of aryl, biaryl, and aryl alkynyl substituted polycyclic tetrahydropyrimidmium, diazepanium, and diazocanium derivatives with moderate-to-high yields. Appropriately functionalized pyridinium templates for these syntheses were obtained under microwave irradiation, using basic alumina as the solid support.