Enantioselective synthesis of dihydrofuranylglycine, furanylglycine, furanylalanine and homo-furanylalanine derivatives

摘要

Enantiomerically pure nor-furanomycin, furanylglycine, furanylalanine and homo-furanylalanine derivatives were prepared from appropriate amino acid derived dienes using ring-closing metathesis as the key step.