Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions

Mohammadizadeh MR; Hasaninejad A; Bahramzadeh M

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Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions

机译：三氟乙酸在微波辅助，无溶剂条件下作为一锅四组分合成1,2,4,5-四取代的咪唑的高效催化剂

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摘要

An efficient method for synthesis of various tetrasubstituted imidazoles, using trifluoroacetic acid (TFA) as a catalytic support, by four-component condensation of benzil, aldehydes, amines, and ammonium acetate under microwave-irradiated, solvent-free conditions is described.

机译：描述了一种有效的合成各种四取代的咪唑的方法，该方法使用三氟乙酸（TFA）作为催化载体，在微波辐射，无溶剂的条件下，通过苯，醛，胺和乙酸铵的四组分缩合反应。

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《Synthetic Communications》 |2009年第18期|共11页
作者
Mohammadizadeh MR; Hasaninejad A; Bahramzadeh M;
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正文语种 eng
中图分类有机化学;
关键词
Four-component; microwave; solvent-free; tetrasubstituted imidazoles; trifluoroacetic acid;

机译：四组分;微波;无溶剂;四取代的咪唑;三氟乙酸;

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1. Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions [J] . Synthetic Communications . 2009,第18期

机译：三氟乙酸在微波辅助，无溶剂条件下作为一锅四组分合成1,2,4,5-四取代的咪唑的高效催化剂
2. Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions [J] . Mohammadizadeh MR, Hasaninejad A, Bahramzadeh M Synthetic Communications . 2009,第16a18期

机译：三氟乙酸在微波辅助，无溶剂条件下作为一锅四组分合成1,2,4,5-四取代的咪唑的高效催化剂
3. Glutamic acid as an efficient and green catalyst for the one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles under thermal, solvent-free conditions [J] . Feizabad Fahimeh Khazaee, Khandan-Barani Khatereh, Hassanabadi Alireza Journal of chemical research: reviews and research papers from all branches of chemistry . 2017,第11期

机译：谷氨酸作为1,2,4,5-四氢咪唑的1,2,4,5-四取代的咪唑，无效，无溶剂条件下的一种有效和绿色催化剂
4. Highly efficient, one-pot, solvent-free synthesis of highly substituted imidazoles using molecular iodine as catalyst [C] . Yi-Ming Ren, Chun Cai International Conference on Chemical, Material and Metallurgical Engineering . 2012

机译：使用分子碘作为催化剂高效，单罐，无溶剂合成高度取代的咪唑
5. New developments toward the synthesis of heterocycles and applications in green chemistry. I. A simple and essentially one-pot synthesis of N-aminated heterocycles using phase transfer catalyst (Aliquat-336). II. Synthesis of pharmaceutically important pyrrole derivatives. III. Applications in green chemistry: Surfactant-mediated environmentally friendly cleavage of aromatic esters and trans-esterification under solvent-free neutral conditions . [D] . Patel, Nitinchandra. 2005

机译：杂环合成的新进展及其在绿色化学中的应用。 I.使用相转移催化剂（Aliquat-336）简单且基本上一锅合成N-胺化的杂环。二。药学上重要的吡咯衍生物的合成。三，在绿色化学中的应用：在无溶剂的中性条件下，表面活性剂介导的环境友好的芳族酯裂解和酯交换反应。
6. p-Sulfonic Acid Calix4arene as an Efficient Catalyst for One-Pot Synthesis of Pharmaceutically Significant Coumarin Derivatives under Solvent-Free Condition [O] . Hamed Tashakkorian, Moslem Mansour Lakouraj, Mona Rouhi 2015

机译：对-磺酸杯4芳烃在无溶剂条件下一锅合成重要药学上香豆素衍生物的高效催化剂
7. Efficient one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles using SBA-Pr-SO3H as a green nano catalyst [O] . Ghodsi Mohammadi Ziarani, Alireza Badiei, Negar Lashgari, 2016

机译：使用sBa-pr-sO3H作为绿色纳米催化剂，有效一锅法合成2,4,5-三取代和1,2,4,5-四取代咪唑

Trifluoroacetic Acid as an Efficient Catalyst for One-Pot, Four-Component Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles Under Microwave-Assisted, Solvent-Free Conditions

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