Optimizing Paced Ventricular Function in Patients with and without Repaired Congenital Heart Disease by Contractility-Guided Lead Implant

摘要

BackgroundThis study evaluates the concept of optimizing ventricular pacing in regard to functional cardiac response. Lead implant based on physiologic variables of contractility at various sites was performed in patients with and without congenital heart disease (CHD). Since right ventricular apical pacing may adversely alter contractility and myocellular function, septal and outflow tract pacing have been advocated. However, there are few studies in the young and essentially none in those with CHD.