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Temporary endoscopic metallic stent for idiopathic esophageal achalasia

机译:临时内镜金属支架治疗特发性食管oph门失弛缓

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Idiopathic achalasia is a motor disorder of the esophagus of unknown etiology caused by loss of motor neurons determining an altered motility. It may determine severe symptoms such as progressive dysphagia, regurgitations, and pulmonary aspirations. Many therapeutic options may be offered to patients with achalasia, from surgery to endoscopic treatments such as pneumatic dilation, botulinum injection, peroral endoscopic myotomy, or endoscopic stenting. Recently, temporary placement of a stent was proposed by Cheng as therapy for achalasia disorders, whereas no Western authors have dealt with it up to date. The present study reports our preliminary experience in 7 patients with achalasia treated with a temporary stent. Partially covered self-expanding metallic stents (Micro-Tech, Nanjin, China) 80 mm long and 30 mm wide were placed under fluoroscopic control and removed after 6 days. Clinical follow-up was scheduled to check endoscopic success, symptoms release, and complications. The placement and the removal of the stents were obtained in all patients without complications. Mean clinical follow-up was 19 months. Five out of 7 patients referred total symptoms release and 2 experienced significant improvement of dysphagia. The procedure was not time consuming and was safe; no mild or severe complications were registered. In conclusion, our results may suggest a possible safe and effective endoscopic alternative treatment in patients with achalasia; however, further larger studies are necessary to confirm these promising, but very preliminary, data.
机译:特发性门失弛缓症是一种病因不明的食道的运动障碍,由运动神经元的丧失决定了运动性的改变。它可以确定严重的症状,例如进行性吞咽困难,反流和肺误吸。从手术到内窥镜治疗,例如气动扩张,肉毒杆菌注射,经口内镜下肌切开术或内镜支架术,可以为失弛缓症患者提供许多治疗选择。最近,Cheng提出临时放置支架作为治疗失弛缓症的方法,而迄今为止,西方没有作者对此进行过处理。本研究报告了我们在7例临时支架治疗的门失弛缓患者中的初步经验。将80 mm长和30 mm宽的部分覆盖的自膨胀金属支架(Micro-Tech,中国南京)置于荧光镜控制下,并在6天后取出。计划进行临床随访,以检查内窥镜检查是否成功,症状缓解和并发症。所有患者均获得了支架的放置和移除,无并发症。平均临床随访时间为19个月。 7例患者中有5例完全缓解症状,2例吞咽困难得到明显改善。该过程既费时又安全。没有发现轻度或严重并发症。总之,我们的结果可能提示门失弛缓症患者可能进行安全有效的内镜替代治疗。但是,有必要进行更大规模的研究,以确认这些有希望但非常初步的数据。

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