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Does prophylactic stent insertion to the common bile duct during endoscopic retrograde cholangiopancreatography (ERCP) before cholecystectomy have any impact on the rate of biliary complications?

机译:胆囊切除术前内镜逆行胰胆管造影术(ERCP)期间预防性支架插入胆总管是否对胆道并发症发生率有影响?

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Background: Patients with choledochocystolithiasis generally undergo endoscopic sphincterotomy (ES) followed by elective cholecystectomy. They can experience the development of recurrent biliary events while waiting for their scheduled surgery. Aim: This study investigated whether stent insertion before cholecystectomy influences the rate of complications. Methods: The study compared retrospective and prospective groups of patients with choledochocystolithiasis who underwent ES with or without prophylactic common bile duct stent insertion before cholecystectomy. The rate of emergency cholecystectomies and biliary complications during the waiting period before the elective procedure was analyzed. Results: For the study, 162 patients with choledochocystolithiasis who underwent endoscopic retrograde cholangiopancreatography (ERCP) with ES were divided to two subgroups. Group A included 52 patients with stent insertion (mean age, 58.3 ± 19.4 years), and group B included 110 patients with no stent insertion (mean age, 61.4 ± 17.7 years) (p = 0.32). Males made up 33.3 % of group A and 53.7 % of group B (p = 0.018). The median time to elective cholecystectomy (open or laparoscopic) was 41.5 days for the patients without bile duct stent insertion before cholecystectomy and 53.5 days for the patients who had the stent insertion before cholecystectomy (p = 0.63). Repeat emergency ERCP due to acute cholangitis was 5.6 % in group A and 1.0 % in group B (p = 0.43). Emergency cholecystectomy rates due to acute cholecystitis after ES were 15.4 % in group A and 14.5 % in group B (p = 1.00). No mortality occurred. Conclusions: According to the study findings, prophylactic stent insertion during ERCP before cholecystectomy has no impact on biliary complications.
机译:背景:胆总管结石症患者通常接受内镜括约肌切开术(ES),然后进行择期胆囊切除术。他们可以在等待安排的手术的同时体验到复发性胆道事件的发展。目的:这项研究调查了在胆囊切除术之前插入支架是否会影响并发症发生率。方法:本研究比较了回顾性和前瞻性两组胆囊切除术前接受或不接受预防性胆总管支架置入术的胆总管结石症患者。分析了择期手术前等待期间的紧急胆囊切除术和胆道并发症发生率。结果:本研究将162例行ES内镜逆行胰胆管造影(ERCP)并伴有ES的胆总管结石症患者分为两个亚组。 A组包括52例有支架置入的患者(平均年龄58.3±19.4岁),B组包括110例无支架置入的患者(平均年龄61.4±17.7岁)(p = 0.32)。男性占A组的33.3%和B组的53.7%(p = 0.018)。对于在胆囊切除术前未插入胆管支架的患者,择期胆囊切除术(开放或腹腔镜)的中位时间为41.5天,而在胆囊切除术前已插入支架的患者为53.5天(p = 0.63)。由于急性胆管炎而再次发生的紧急ERCP在A组为5.6%,在B组为1.0%(p = 0.43)。 ES后急性胆囊炎导致的紧急胆囊切除术发生率,A组为15.4%,B组为14.5%(p = 1.00)。没有死亡发生。结论:根据研究结果,胆囊切除术前在ERCP期间预防性支架置入对胆道并发症没有影响。

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