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Analysis of Toxic Trace Metals in Pet Foods Using Cryogenic Grinding and Quantitation by ICP-MS, Part II

机译:ICP-MS低温研磨和定量分析宠物食品中的痕量金属

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This article is the second part of a study that examines pet foods from a variety of sources to determine if there were potentially toxic elements present in the foods and also whether more expensive foods with higher quality ingredients equated to lower levels of toxic elements. A range of "budget" to "premium" grade pet foods samples were donated by pet owners or purchased in several different stores. The food samples were ground in a cryogenic freezer mill (dry samples) or blender (wet samples), digested with concentrated nitric acid, and analyzed for trace-metals content by inductively coupled plasma-mass spectrometry (ICP-MS). Results were then compared to Environmental Protection Agency Reference Dose (RfD) values and World Health Organization Tolerable Daily Intake (TDI) values, which are considered the daily oral exposure limits for the human population. Human limits were scaled to the weight of a 50-lb dog or 10-lb cat to gain perspective of an animal's potential exposure. Many of the pet foods sampled showed significant concentrations of various toxic metals. In many cases, the concentrations exceeded the extrapolated human limit values calculated to pet-size dosages.
机译:本文是研究的第二部分,该研究检查了来自各种来源的宠物食品,以确定食品中是否存在潜在的有毒元素,以及具有较高质量成分的较昂贵食品是否等于较低水平的有毒元素。宠物主人捐赠了一系列“预算”至“高级”等级的宠物食品样本,或在数家不同的商店购买了这些样本。将食品样品在低温冷冻机(干样品)或搅拌器(湿样品)中研磨,用浓硝酸消化,并通过电感耦合等离子体质谱法(ICP-MS)分析痕量金属的含量。然后将结果与环境保护局参考剂量(RfD)值和世界卫生组织可耐受的每日摄入量(TDI)值进行比较,这被认为是人类每天的口服暴露极限。将人类极限值缩放为50磅狗或10磅猫的重量,以了解动物的潜在暴露情况。采样的许多宠物食品都显示出高浓度的各种有毒金属。在许多情况下,浓度超过了根据宠物大小剂量计算出的推断人类极限值。

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