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Stem cells in the umbilical cord.

机译:脐带干细胞。

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摘要

Stem cells are the next frontier in medicine. Stem cells are thought to have great therapeutic and biotechnological potential. This will not only to replace damaged or dysfunctional cells, but also rescue them and/or deliver therapeutic proteins after they have been engineered to do so. Currently, ethical and scientific issues surround both embryonic and fetal stem cells and hinder their widespread implementation. In contrast, stem cells recovered postnatally from the umbilical cord, including the umbilical cord blood cells, amnion/placenta, umbilical cord vein, or umbilical cord matrix cells, are a readily available and inexpensive source of cells that are capable of forming many different cell types (i.e., they are "multipotent"). This review will focus on the umbilical cord-derived stem cells and compare those cells with adult bone marrow-derived mesenchymal stem cells.
机译:干细胞是医学的下一个前沿领域。干细胞被认为具有巨大的治疗和生物技术潜力。这不仅可以替换受损或功能异常的细胞,还可以在工程改造后拯救它们和/或递送治疗性蛋白质。当前,伦理和科学问题围绕着胚胎干细胞和胎儿干细胞,并阻碍了它们的广泛应用。相反,出生后从脐带中回收的干细胞,包括脐带血细胞,羊膜/胎盘,脐带静脉或脐带基质细胞,是一种易于获得且廉价的能够形成许多不同细胞的细胞来源。类型(即它们是“多能的”)。这篇综述将集中于脐带来源的干细胞,并将这些细胞与成年骨髓来源的间充质干细胞进行比较。

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