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Review of methods used for quantifying excess water in over-hydrated skin using evaporimetry.

机译:使用蒸发法量化过度水合皮肤中多余水分的方法综述。

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摘要

BACKGROUND: Advances in diapers and skin barrier products are often aimed at reducing water penetration of the skin to prevent diaper dermatitis and evaporimetry has commonly been measured to quantify excess water in the skin. The aim of this study was to critically review the methods used to measure water vapour flux density (WVFD) using evaporimetry in order to identify a standardised methodology. METHODS: We used MEDLINE (1980-2008) and hand searching to identify published papers that used evaporimetry to measure WVFD when the skin has been exposed to water/saline/urine. We compared the papers with respect to subjects, sites, methods of hydrating the skin, the conditions of logging, timing and analysing the evaporimetry data. RESULTS: We identified 10 papers. Methods and techniques for measuring WVFD and analysing data varied considerably between studies and it was not possible to identify a standardised method. The main sources of error and variation are discussed. CONCLUSION: Little work has been carried out to establish the optimum methods and techniques needed to minimise variation in measurements of WVFD using evaporimetery. There is a need to develop more robust, standardised methods and to demonstrate their reliability for further work.
机译:背景:尿布和皮肤屏障产品的进步通常旨在减少皮肤的水渗透,以防止尿布皮炎,并且蒸发法通常被用来量化皮肤中多余的水分。这项研究的目的是批判性地审查使用蒸发法测量水蒸气通量密度(WVFD)的方法,以便确定标准化方法。方法:我们使用MEDLINE(1980-2008)进行手工搜索,以找出已发表的论文,这些论文在皮肤暴露于水/盐水/尿液后使用蒸发法测量WVFD。我们比较了有关主题,部位,保湿皮肤的方法,测井条件,计时和蒸发数据分析方面的论文。结果:我们鉴定了10篇论文。在研究之间,用于测量WVFD和分析数据的方法和技术差异很大,因此无法确定标准化方法。讨论了误差和变异的主要来源。结论:为建立最小化使用蒸发仪测量WVFD的变化所需的最佳方法和技术,开展的工作很少。需要开发更强大的标准化方法,并证明其可靠性以进行进一步的工作。

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