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首页> 外文期刊>Sexually Transmitted Infections >Sexually transmitted infections in male clients of female sex workers in Benin: risk factors and reassessment of the leucocyte esterase dipstick for screening of urethral infections.
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Sexually transmitted infections in male clients of female sex workers in Benin: risk factors and reassessment of the leucocyte esterase dipstick for screening of urethral infections.

机译:贝宁女性工作人员男性客户的性传播感染:危险因素和白细胞酯酶试纸的重新评估,以筛查尿道感染。

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摘要

OBJECTIVES: (1) To assess risk factors for urethral infections with Chlamydia trachomatis, Neisseria gonorrhoeae, and Trichomonas vaginalis among male clients of female sex workers (FSWs) in Benin; (2) to study the validity of LED testing of male urine samples compared to a highly sensitive gold standard (PCR) for the diagnosis of urethral infections with the organisms cited above. METHODS: Male clients of FSWs (n=404) were recruited on site at prostitution venues in Cotonou, Benin, between 28 May and 18 August 1998. A urine sample was obtained from each participant just before he visited the FSW, and tested immediately using a leucocyte esterase dipstick (LED) test. It was then tested for HIV using the Calypte EIA with western blot confirmation, and for C. trachomatis, N. gonorrhoeae, and T. vaginalis by PCR. After leaving the FSW's room, participants were interviewed about demographics, sexual behaviour, STI history and current symptoms and signs, and were examined for urethral discharge, genital ulcers, and inguinal lymphadenopathies. RESULTS: STI prevalences were: C. trachomatis, 2.7%; N. gonorrhoeae, 5.4%; either chlamydia or gonorrhoea 7.7%; T. vaginalis 2.7%; HIV, 8.4%. Lack of condom use with FSWs and a history of STI were independently associated with C. trachomatis and/or N. gonorrhoeae infection. Over 80% of these infections were in asymptomatic subjects. The overall sensitivity, specificity, positive and negative predictive values of the LED test for detection of either C. trachomatis or N. gonorrhoeae were 48.4%, 94.9%, 44.1%, and 95.7%, respectively. In symptomatic participants (n=22), all these parameters were 100% while they were 47.4%, 94.7%, 37.5%, and 96.4% in asymptomatic men (n=304). CONCLUSIONS: Since most STIs are asymptomatic in this population, case finding programmes for gonorrhoea and chlamydia could be useful. The performance characteristics of the LED test in this study suggest that it could be useful to detect asymptomatic infection by either C. trachomatis or N. gonorrhoeae in high risk men.
机译:目的:(1)评估贝宁女性性工作者(FSWs)男性客户中沙眼衣原体,淋病奈瑟氏球菌和阴道滴虫的尿道感染的危险因素; (2)研究与高灵敏度金标准(PCR)相比,男性尿液样品的LED检测在诊断上述生物引起的尿道感染中的有效性。方法:1998年5月28日至8月18日在贝宁科托努的卖淫场所现场招募了FSW的男性顾客(n = 404)。就在每位参与者访问FSW之前,都从他们身上采集了尿液样本,并立即使用白细胞酯酶试纸(LED)测试。然后使用Calypte EIA进行Western blot验证,以检测HIV感染情况,并通过PCR检测沙眼衣原体,淋病奈瑟氏球菌和阴道锥虫。在离开FSW的房间后,对参与者进行人口统计学,性行为,性传播感染史以及当前症状和体征的访谈,并检查尿道分泌物,生殖器溃疡和腹股沟淋巴腺病。结果:性传播感染患病率:沙眼衣原体为2.7%;沙眼衣原体为2.7%。淋病奈瑟氏球菌5.4%;衣原体或淋病7.7%;阴道T.2.7%;艾滋病毒占8.4%。缺乏与FSW一起使用安全套和性病史与沙眼衣原体和/或淋病奈瑟氏球菌感染独立相关。这些感染中有80%以上是无症状的。 LED检测沙眼衣原体或淋病奈瑟氏球菌的总体灵敏度,特异性,阳性和阴性预测值分别为48.4%,94.9%,44.1%和95.7%。在有症状的参与者(n = 22)中,所有这些参数均为100%,而在无症状的男性(n = 304)中,它们分别为47.4%,94.7%,37.5%和96.4%。结论:由于大多数性传播感染在该人群中无症状,因此针对淋病和衣原体的病例发现计划可能会有用。这项研究中LED测试的性能特征表明,在高危男性中检测沙眼衣原体或淋病奈瑟菌的无症状感染可能是有用的。

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