Changes in incidence of anogenital warts diagnoses after the introduction of human papillomavirus vaccination in germany-an ecologic study

摘要

In a large health insurance database in Germany, incidence of anogenital warts among 15-to 19-year-old females decreased from 316/100,000 person-years in 2007 to 242 in 2008 (23% reduction, P = 0.0001). The decrease started between the first and second quarter of 2007 (human papillomavirus vaccination was introduced in March 2007).