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Development of Relevant Non-human Primate Models A New Research Platform for Neuroinflammatory Disease

机译:相关的非人类灵长类动物模型的开发神经炎性疾病的新研究平台

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The successful development of biotechnology-derived pharma-ceuticals critically depends on the availability of relevant animal models in which the safety and efficacy can be tested. As the high species specificity often precludes testing in the standard rodent I models there is a growing need for validated disease models in species more closely related to man, i.e. non-human primates. In this publication we present a new precompetitive research consortium comprising scientists from academia and drug development industry who will collaborate on the cost-effective development of well-validated and clinically relevant disease models.
机译:生物技术衍生的药品的成功开发,关键取决于相关动物模型的可用性,可以在其中测试安全性和功效。由于高物种特异性通常排除了在标准啮齿动物I模型中进行测试的需要,因此越来越需要与人类(即非人类灵长类动物)更紧密相关的物种中经过验证的疾病模型。在本出版物中,我们提出了一个新的竞争前研究联盟,由来自学术界和药物开发行业的科学家组成,他们将在经济有效地开发经过充分验证的临床相关疾病模型上进行合作。

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