首页> 外文期刊>Seminars in fetal & neonatal medicine >Specific complications of monochorionic twin pregnancies: twin-twin transfusion syndrome and twin reversed arterial perfusion sequence.
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Specific complications of monochorionic twin pregnancies: twin-twin transfusion syndrome and twin reversed arterial perfusion sequence.

机译:单绒毛膜双胎妊娠的特殊并发症:双胎双输血综合征和双反动脉灌注序列。

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摘要

Monochorionic twins are subjected to specific complications which originate in either imbalance or abnormality of the single placenta serving two twins. This unequal placental sharing can cause complications including twin-twin transfusion syndrome (TTTS), twin anemia-polycythemia sequence (TAPS), selective intrauterine growth restriction or twin reversed arterial perfusion sequence (TRAP). Monochorionicity also makes the management of these specific complications as well as that of a severe malformation in one twin hazardous since the spontaneous death of one twin exposes the co-twin to a risk of exsanguination into the dead twin and its placenta. The latter is responsible for the death of the co-twin in up to 20% of the cases and in ischemic sequelae in about the same proportions in the survivors. Although the symptoms of all these complications are very different, the keystone of their management comes down to either surgical destruction of the inter-twin anastomoses on the chorionic plate when aiming at dual survival or selective and permanent occlusion of the cord of a severely affected twin aiming at protecting the normal co-twin. This can be best achieved by fetoscopic selective laser coagulation and bipolar forceps cord coagulation respectively.
机译:单绒毛膜双胞胎遭受特定的并发症,该并发症源于服务两个双胞胎的单个胎盘的失衡或异常。这种不平等的胎盘共享可能导致并发症,包括双胎双输血综合征(TTTS),双胎贫血-红细胞增多症序列(TAPS),选择性子宫内生长受限或双胎反向动脉灌注序列(TRAP)。单绒毛膜性还使这些双胞胎的这些特殊并发症以及严重畸形的处理变得危险,因为一个双胞胎的自发死亡使同卵双胞胎有放血到死双胞胎及其胎盘的危险。后者在多达20%的病例中导致共同双胞胎的死亡,在缺血性后遗症中幸存者的比例大致相同。尽管所有这些并发症的症状都有很大不同,但其治疗的重点在于针对双重生存或严重受累双胞胎的脐带选择性永久性闭塞的手术破坏了绒毛膜上双胞胎间吻合的手术。旨在保护正常的双胞胎。这可以分别通过胎儿镜选择性激光凝结和双极镊子脐带凝结来最好地实现。

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