Intravenous non-opioids for immediate postop pain relief in day-case programmes: Paracetamol (acetaminophen) and ketorolac are good choices reducing opioid needs and opioid side-effects

摘要

In this issue of the Scandinavian Journal of Pain Anand et al. report on their study comparing intravenous 1 g of paracetamol (acetaminophen) (Perfalgan~R in the Nordic countries Ofirmev~R in the USA) with intravenous 30 mg ketorolac (Toradol~R) given during the procedure in order to reduce pain in the immediate post-anaesthesia/post-operative period [1 ]. They found no difference in the first half-hour, but after 45 min the pain intensity was somewhat less in the ketorolac treated patients who had an ambulatory parathyroidectomy. Opioid use for rescue analgesia was not different, but there was a bit more nausea in the paracetamol-treated patients [1].