(Q)SARs: gatekeepers against risk on chemicals?

摘要

ECOSAR and DEREKfW predictions for the (eco)toxicological effects of circa 70 substances were compared with experimental data for risk assessment purposes. These and other (quantitative) structure - activity relationships ((Q)SARs) programs will playan important role in future chemical policies, such as in the European Union and The Netherlands, to reduce animal testing and costs and to speed up the number of risk assessments for hazardous chemicals. The two programs. ECOSAR and DEREKfW. were selected because they are easy to use and transparent in their predictions. They predict to which chemical class a substance belongs and also predict some (eco)toxicological properties.