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Factors That Predict Blood Loss After Bernese Periacetabular Osteotomy

机译:伯尔尼髋臼周围截骨术后预测失血的因素

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Although strategies to reduce bleeding and avoid allogeneic transfusion have been described, there is controversy about the factors associated with blood loss after Bernese periacetabular osteotomy. This study was conducted to determine risk factors for postoperative blood loss. After institutional review board approval was obtained, a retrospective review was conducted of 41 young patients who underwent periacetabular osteotomy for symptomatic acetabular dysplasia over a 3-year period. Of these patients, two-thirds donated blood before surgery. A Cell Saver Elite autotransfusion system (Haemonetics, Braintree, Massachusetts) was used intraoperatively in all cases. Hemoglobin and hematocrit were obtained before surgery and during the hospital stay. The primary outcome variable was the percentage of total blood volume lost during surgery. Univariate analysis was performed to test the association between potential predictors of blood volume loss. Candidate variables that were significant at alpha=0.15 were tested with multivariate analysis. The average percentage of blood volume lost during surgery was 30.3% (95% confidence interval, 25.1%-35.5%). Univariate analysis showed that operative time, arthrotomy, femoral head-neck osteochondroplasty, labral procedure, male sex, and age were prognostic factors associated with increased blood volume loss. However, operative time (average, 294.6 minutes; range, 204-444 minutes) was the only independent predictor of increased blood loss in the final model. Additional procedures, such as femoral head-neck osteochondroplasty and labral repair or debridement performed through an anterior hip arthrotomy at the time of periacetabular osteotomy, were associated with increased operative time. The findings suggest that all patients undergoing periacetabular osteotomy, including those having concomitant procedures, may benefit from pre- and intraoperative strategies to conserve blood and avoid allogeneic transfusion.
机译:尽管已经描述了减少出血和避免异体输血的策略,但是关于伯尔尼髋臼周围截骨术后失血相关因素的争论仍然存在。进行这项研究是为了确定术后失血的危险因素。在获得机构审查委员会的批准之后,对41例因髋臼异型增生3年而接受髋臼周围截骨术的年轻患者进行了回顾性审查。在这些患者中,三分之二在手术前献血。所有病例均在手术中使用了Cell Saver Elite自体输血系统(Haemonetics,Braintree,马萨诸塞州)。手术前和住院期间均获得了血红蛋白和血细胞比容。主要的结果变量是手术期间流失的总血量的百分比。进行单变量分析以检验潜在的血容量损失预测因子之间的关联。使用多变量分析测试了alpha = 0.15时有效的候选变量。手术期间平均失血百分比为30.3%(95%置信区间,25.1%-35.5%)。单因素分析表明,手术时间,关节切开术,股骨头颈软骨置换术,阴唇手术,男性和年龄是与失血量增加相关的预后因素。但是,手术时间(平均294.6分钟;范围204-444分钟)是最终模型中失血增加的唯一独立预测因子。进行髋臼周围截骨术时需要进行其他手术,例如股骨头颈椎破骨术和通过前髋关节置换术进行阴唇修复或清创术,这与手术时间增加有关。研究结果表明,所有接受髋臼切开术的患者,包括那些同时进行手术的患者,都可能受益于术前和术中策略以节约血液并避免异体输血。

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