Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

Phillips K. L. E.; Cullen K.; Chiverton N.; Michael A. L. R.; Cole A. A.; Breakwell L. M.; Haddock G.; Bunning R. A. D.; Cross A. K.; Le Maitre C. L.

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Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

机译：细胞因子和趋化因子在人椎间盘退变中的潜在作用：白细胞介素-1是分解代谢过程的主要调节剂

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Objective: These studies investigated cytokine and chemokine receptor profiles in nucleus pulposus (NP) cells, and the effects of receptor stimulation on mRNA levels of extracellular matrix (ECM) components, degrading enzymes and cytokine and chemokine expression.

机译：目的：这些研究调查了髓核（NP）细胞中的细胞因子和趋化因子受体概况，以及受体刺激对细胞外基质（ECM）组分，降解酶，细胞因子和趋化因子表达的mRNA水平的影响。

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《Osteoarthritis and cartilage》 |2015年第7期|共13页
作者
Phillips K. L. E.; Cullen K.; Chiverton N.; Michael A. L. R.; Cole A. A.; Breakwell L. M.; Haddock G.; Bunning R. A. D.; Cross A. K.; Le Maitre C. L.;
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正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
Cytokine; Chemokine receptors; Intervertebral disc degeneration; Interleukin-1;

机译：细胞因子;趋化因子受体;椎间盘退变;白介素-1;

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1. Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes [J] . Phillips K. L. E., Cullen K., Chiverton N., Osteoarthritis and cartilage . 2015,第7期

机译：细胞因子和趋化因子在人椎间盘退变中的潜在作用：白细胞介素-1是分解代谢过程的主要调节剂
2. The elastic fibre network of the human lumbar anulus fibrosus: architecture, mechanical function and potential role in the progression of intervertebral disc degeneration. [J] . Smith LJ, Fazzalari NL European spine journal: official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society . 2009,第4期

机译：人腰椎纤维环的弹性纤维网络：结构，力学功能和潜在的作用在椎间盘退变的进展。
3. The elastic fibre network of the human lumbar anulus fibrosus: architecture, mechanical function and potential role in the progression of intervertebral disc degeneration [J] . Lachlan J. Smith, Nicola L. Fazzalari European Spine Journal . 2009,第4期

机译：人腰椎肛门纤维的弹性纤维网络：结构，力学功能和潜在的作用在椎间盘退变的进展。
4. Effect of aging and degeneration on the human intervertebral disc during the diurnal cycle: A finite element study [C] . Massey C.J., van Donkelaar C.C., Marcolongo M. IEEE Annual Northeast Bioengineering Conference . 2010

机译：日循环中衰老和变性对人椎间盘的影响：有限元研究
5. Characterizing Human Bone Marrow Derived Mesenchymal Stem Cell Exosomes and the Effects of Varying Oxygen Tension in the Preconditioning Environment as a Potential Therapeutic for Intervertebral Disc Degeneration [D] . ?Chionuma, Henry N. 2020

机译：表征人骨髓衍生的间充质干细胞外泌体及不同氧张力在预处理环境中的影响作为椎间盘变性的潜在治疗方法
6. The role of interleukin-1 in the pathogenesis of human Intervertebral disc degeneration [O] . Christine Lyn Le Maitre, Anthony J Freemont, Judith Alison Hoyland 2005

机译：白细胞介素-1在人类椎间盘退变的发病机制中的作用
7. Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes [O] . Phillips K.L.E., Cullen K., Chiverton N., 2015

机译：细胞因子和趋化因子在人椎间盘退变中的潜在作用：白细胞介素-1是分解代谢过程的主要调节剂

Potential roles of cytokines and chemokines in human intervertebral disc degeneration: interleukin-1 is a master regulator of catabolic processes

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