A facile solvent free microwave induced synthesis of chlorine containing pyrazoline and Isoxazoline derivatives and their phytotic impact on some flowering plants and antimicrobial activity

摘要

Eight New chlorine containing 4-Aroyl/Alkoyl-Δ~2-pyrazolines and isoxazolines have been synthesized with 80-85% yield by a microwave promoted solvent-free condensation of 3-aroyl/ alkoylflavanones 5a-d respectively with phenylhydrazine hydrochloride and hydroxylaminehydrochloride over potassium carbonate The work-up is simple and involves treatment with ice-cold water. A considerable increase in the reaction rate has been observed, with better yields.