Demethylation of coordinated hexamethylbenzene. Carbon-carbon bond activation during ruthenium-mediated [3+2] allyl alkyne cycloaddition reactions

摘要

The demethylation. of coordinated hexamethylbenzene is integrated into [3 + 2] allyl/alkyne cycloaddition reactions mediated by (eta(6)-hexamethylbenzene)-Ru(eta(3)-allyl)OTf. The reaction proceeds in high yield at or below room temperature and yields methane and (eta(6)-pentamethylbenzene)ruthenium(1,2-dialkylcyclopentadienyl)+OTf- complexes exclusively. Cycloaddition, with carbon-carbon bond activation, is general for a range of disubstituted alkynes. [References: 50]