Synthesis and characterization of 2-(4-bromophenyl)-1H- benzimidazole and 2-(6-bromochroman-2-yl)-1H- benzimidazole compounds

摘要

N-alkyl, N-carboxylate andN-sulfonyl compounds of 2-(4-bromophenyl)-1H-benzimidazole and 2-(6-bromochroman-2-yl)-1H-benzimidazole, using alkyl halides, alkyl chloroformates and sulfonyl chlorides, respectively have been synthesized in high yields using different polymer-supports and different solvents. The advantages of this simple and rapid method are extremely mild conditions, easy work-up and clean reaction without undesired byproducts.