Total Synthesis of Carbazoquinocin C: Application of the o-Benzannulation of Fischer Carbene Complexes to Carbazole-3,4-quinone Alkaloids

摘要

The photoinduced o-benzannulation of 3-(2-vinyl)indolylcarbene complexes provides a direct route to carbazole derivatives that are oxygenated in the 3- and 4-positions. This reaction is quite efficient and provides for a unique synthesis of the lipid peroxidation inhibitor carbazoquinocin C.