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Gefitinib in combination with prednisolone to avoid interstitial lung disease during non-small cell lung cancer treatment: A case report

机译:吉非替尼联合泼尼松龙在非小细胞肺癌治疗中避免间质性肺疾病:一例报告

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摘要

Gefitinib-induced interstitial lung disease (ILD) is a rare but lethal drug adverse event, which usually leads to the withdrawal of gefitinib and causes complications with anticancer treatment. In this study, gefitinib administration combined with prednisolone in a female with stage IIIb non-small cell lung cancer (NSCLC) produced a good outcome without inducing ILD. The results suggested that combined administration of gefitinib with glucocorticoids may be an efficient method to treat NSCLC while avoiding complications with ILD.
机译:吉非替尼诱发的间质性肺病(ILD)是一种罕见但致命的药物不良事件,通常会导致吉非替尼停药并引起抗癌治疗并发症。在这项研究中,吉非替尼联合泼尼松龙在IIIb期非小细胞肺癌(NSCLC)女性中给药可产生良好的预后,而不会诱发ILD。结果表明,吉非替尼与糖皮质激素联合给药可能是治疗NSCLC的有效方法,同时避免了ILD并发症。

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