'Derivatives of 1,1,2,2-Tetraaminoethane.Condensation of 1,2-Diacetoxy-1,2-bis(ethoxycarbonylamino)ethane and l-Acetoxy-1,2,2-tris(ethoxycarbonylamino)ethane with Nitrogen-Containing Nucleophiles

摘要

We formerly established that N,N',N",N'"-tetraacyl derivatives of 1,1,2,2-tetraaminoethane can be obtained from 1,2-diacetoxy-1,2-bis(acylamino)ethanes and nitrogen-containing nucleophiles in anhydrous medium.In the present study a possibility is demonstrated to apply a similar approach to the synthesis of substituted 1,1,2,2-tetraaminoethanes by an example of a condensation of 1,2-diacetoxy-1,2-bis(ethoxycarbonylamino)ethane(III)and 1-acetoxy-1,2,2-tris(ethoxycarbonylamino)-ethane(IV)with acetamide,urethane,and low-basic amines of the furazan series(diaminofurazan and 4-phenyl-3-furazanylamine).