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A risk adjusted cost-effectiveness analysis of alternative models of nurse involvement in obesity management in primary care

机译:初级保健中肥胖管理中护士参与替代模式的风险调整后成本效益分析

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Objective: Controlled evaluations are subject to uncertainty regarding their replication in the real world, particularly around systems of service provision. Using routinely collected data, we undertook a risk adjusted cost-effectiveness (RAC-E) analysis of alternative applied models of primary health care for the management of obese adult patients. Models were based on the reported level of involvement of practice nurses (registered or enrolled nurses working in general practice) in the provision of clinical-based activities. Design and Methods: Linked, routinely collected clinical data describing clinical outcomes (weight, BMI, and obesity-related complications) and resource use (primary care, pharmaceutical, and hospital resource use) were collected. Potential confounders were controlled for using propensity weighted regression analyses. Results: Relative to low level involvement of practice nurses in the provision of clinical-based activities to obese patients, high level involvement was associated with lower costs and better outcomes (more patients losing weight, and larger mean reductions in BMI). Excluding hospital costs, high level practice nurse involvement was associated with slightly higher costs. Incrementally, the high level model gets one additional obese patient to lose weight at an additional cost of $6,741, and reduces mean BMI by an additional one point at an additional cost of $563 (upper 95% confidence interval $1,547). Conclusion: Converted to quality adjusted life year (QALY) gains, the results provide a strong indication that increased involvement of practice nurses in clinical activities is associated with additional health benefits that are achieved at reasonable additional cost. Dissemination activities and incentives are required to encourage general practices to better integrate practice nurses in the active provision of clinical services.
机译:目标:受控评估在现实世界中的复制是否存在不确定性,尤其是在服务提供系统周围。使用常规收集的数据,我们对用于肥胖成年患者管理的替代性初级卫生保健应用模型进行了风险调整后的成本-效果(RAC-E)分析。模型基于所报告的执业护士(从事全科工作的注册或注册护士)参与提供临床活动的水平。设计与方法:收集定期收集的描述临床结果(体重,BMI和肥胖相关并发症)和资源使用情况(基层医疗,药物和医院资源使用情况)的临床数据。使用倾向加权回归分析来控制潜在的混杂因素。结果:相对于执业护士在肥胖患者中提供基于临床的活动的低水平参与,高水平的参与与较低的成本和更好的结局相关(更多的患者减轻体重,BMI平均降低更大)。除医院费用外,高级执业护士的参与与费用略高有关​​。高级别模型会逐步增加一名肥胖患者的减肥成本,费用为$ 6,741,并使平均BMI降低一点,费用为$ 563(95%置信区间的上限为$ 1,547)。结论:转换为质量调整生命年(QALY)获得的结果有力表明,执业护士更多地参与临床活动与以合理的额外费用获得的其他健康益处有关。需要开展传播活动和激励措施,以鼓励一般做法更好地将执业护士纳入积极提供的临床服务中。

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