An uncommon case of anterior segment dysgenesis in a domestic shorthair cat.

摘要

A case of anterior segment dysgenesis in an 18-month-old, one-eyed, domestic shorthair cat is reported. This congenital anomaly presented with a central corneal coloboma, a microspheric lens with a partial cataract, pupillary membrane remnants and goniodysgenesis. Treatment consisted of lens removal by phacoemulsification and a corneal graft using a porcine small intestinal submucosa biomaterial (Vet BioSISt) to repair the cornea and preserve the vision. Intraocular pressure remained within the normal range. Features of this case warrant classification as Peters' anomaly, first in humans in 1887 and which consists of defective development of the posterior cornea caused by abnormal migration and differentiation of neural crest cells impeded by the late separation of the lens vesicle from the surface ectoderm.