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Epidural analgesia and fetal head malposition at vaginal delivery.

机译:阴道分娩时硬膜外镇痛和胎儿头位置不正。

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摘要

OBJECTIVE: To determine if nulliparas who delivered with on-demand epidural analgesia are more likely to have malpositioning of the fetal vertex at delivery than women delivered during a period of restricted epidural use. METHODS: A retrospective cohort of nulliparous women with spontaneous labor delivered during a 12-month period immediately before the availability of on-demand labor epidural analgesia was compared with a similar group of nulliparas delivered after labor epidural analgesia was available on request. The primary outcome variable was a non-occiput anterior position or malpositioned fetal head at vaginal delivery. RESULTS: The frequency of epidural use increased from 0.9% before epidural analgesia became available on demand to 82.9% afterward. Fetal head malpositioning at vaginal delivery occurred in 26 of 434 (6.0%) women delivered in the before period compared with 29 of 511 (5.7%) in the after period (relative risk 0.95, 95% confidence interval 0.6, 1.6). No statistically significant difference in the incidence of fetal head malpositioning was present after patients were stratified by mode of delivery (Mantel-Haenszel weighted relative risk 0.94, 95% confidence interval 0.6, 1.4). The study sample size provided 85% power to detect a two-fold increase in the incidence of fetal malpositioning from a baseline rate of 6% associated with on-demand epidural use. CONCLUSION: Providing on-request labor epidural analgesia to nulliparas in spontaneous labor did not result in a clinically significant increase in the frequency of fetal head malpositioning at vaginal delivery.
机译:目的:确定在硬膜外使用受限的时期内,按需硬膜外镇痛分娩的原产妇是否比分娩的女性更容易发生胎儿顶点错位。方法:回顾性研究了在按需进行硬膜外镇痛前12个月内分娩的自发分娩妇女的回顾性队列研究,并与根据要求提供硬膜外分娩镇痛后分娩的类似一组原产妇进行了比较。主要结果变量是阴道分娩时非枕前位或胎头位置不正确。结果:硬膜外使用的频率从硬膜外镇痛开始之前的0.9%增加到之后的82.9%。前期分娩的434例女性中有26例(6.0%)发生了阴道分娩时胎头位置不正确,而后段时期的511例中有29例(5.7%)中发生了29例(相对危险度0.95,95%的置信区间0.6、1.6)。按分娩方式分层后,胎儿头部错位发生率在统计学上无统计学差异(Mantel-Haenszel加权相对危险度0.94,95%置信区间0.6,1.4)。研究样本量提供了85%的能力,可检测出与按需硬膜外使用相关的6%的基线比率,胎儿错位发生率增加了两倍。结论:对自然分娩中的原产妇提供按需分娩硬膜外镇痛不会导致阴道分娩时胎头位置异常的发生率出现临床上的显着增加。

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