Patients with early-stage cervical cancer are usually treated with conization or simple hysterectomy without removal of regional lymph nodes. A critical prognostic factor in patients with this cancer is the depth of invasion. Previous studies have reported that conization with frozen section analysis correlates 75% to 100% of the time with the pathologic findings in distinguishing dysplasia from invasive carcinoma. These studies were conducted at single academic centers; their applicability to general practice is unknown.The aims of this retrospective study were to review data from a single tertiary cancer center on the accuracy of conization with intraoperative frozen section analysis and to compare results with those from 2 community hospitals. Data were obtained for women who underwent conization with intraoperative frozen section analysis between 1997 and 2011 at the University of Texas MD Anderson Cancer Center and 2 community hospitals-The Woman's Hospital of Texas and St Luke's Episcopal Hospital. Results of pathologic analysis of frozen sections, loop electrosurgical excisional procedure/ conization specimens, and hysterectomy specimens were compared for each patient.
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