Synthesis of New 4-Phosphorylated Derivatives of 5-Amino-1,3-oxazole

摘要

The N-1,1,1,2-Tetrachloroethylamides were found to react with diethyl amidophosphites via the Arbuzov reaction to afford N-substituted amides of ethyl 1-acylamino-2,2,2-trichloroethylphosphonic acids. A convenient method for the synthesis of new 4-phosphorylated 5-amino-1,3-oxazoles on their basis was developed.