Animation of Calix resorcinarenes. First Synthesis of Calix phenylenediamines

摘要

Calix resorcinarenes form a convenient platform for the construction on their basis of complex macro-heterocyclic and supramolecular systems of different architecture, which is associated with the conformational lability and high reactivity of these compounds. The replacement of the hydroxy groups by other functions will change the properties of the calixarene system and expand the range of basic macrocycles. Here we report the first data on the substitution of hydroxy groups in the molecules of calix resorcin-arenes by amino groups. As substrates for the amination tetranaphthylresorcynarene (Ia), which has a chair conformation with rttt configuration of aryl groups, and tetramethylresorcynarene (Ib) in the crown conformation with rccc configuration of alkyl groups were used. Reactions of resorcinarenes I with ammonia, aniline, and dibutylamine were performed in a CEM "Discover" microwave reactor.