Some Problems of Spontaneous Protein Peroxidation

I.V.Shugalei; S.A.Lukogorshaya; I.V.Tselinskii

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Some Problems of Spontaneous Protein Peroxidation

机译：自发性蛋白质过氧化的一些问题

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摘要

General regularities of spontaneous peroxide fragmentation of polypeptide chains are considered with human serum albumin as a model. A radical chain mechanism of this reaction is proposed. The chain process is initiated by reactin of ionogenic peptide groups with dissolved oxygen.

机译：以人血清白蛋白为模型考虑了多肽链自发性过氧化物断裂的一般规律。提出了该反应的自由基链机理。链过程是由离子肽基团与溶解氧的反应引发的。

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《Russian Journal of General Chemistry》 |2001年第6期|共7页
作者
I.V.Shugalei; S.A.Lukogorshaya; I.V.Tselinskii;
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正文语种 eng
中图分类化学;
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1. Mitogen-activated protein kinase activation by hydrogen peroxide is mediated through tyrosine kinase-dependent, protein kinase C-independent pathways in vascular smooth muscle cells: upregulation in spontaneously hypertensive rats. [J] . Tabet F, Schiffrin EL, Touyz RM Journal of hypertension . 2005,第11期

机译：过氧化氢激活的丝裂原激活的蛋白激酶是通过血管平滑肌细胞中酪氨酸激酶依赖性，蛋白激酶C依赖性途径介导的：自发性高血压大鼠中的上调。
2. Knock-out of SO1377 gene, which encodes the member of a conserved hypothetical bacterial protein family COG2268, results in alteration of iron metabolism, increased spontaneous mutation and hydrogen peroxide sensitivity in Shewanella oneidensis MR-1 [J] . Weimin Gao, Yongqing Liu, Carol S Giometti, BMC Genomics . 2006,第1期

机译：SO1377基因的敲除编码一个保守的假设细菌蛋白家族COG2268的成员，导致Shewanella oneidensis MR-1中铁代谢的改变，自发突变增加和过氧化氢敏感性
3. Suppression of spontaneous and hydrogen peroxide-induced mutations by a MutT-type nucleotide pool sanitization enzyme, the Escherichia coli Orf135 protein. [J] . Kamiya H, Iida E, Murata Kamiya N, Genes to cells : . 2003,第12期

机译：MutT型核苷酸库消毒酶Escherichia coli Orf135蛋白抑制自发和过氧化氢诱导的突变。
4. Identification of proteins modified by the lipid peroxidation aldehyde DODE in MCF7 breast cancer cells. [C] . Peter G. Slade, Michelle V. Williams, Viral Brahmbhtt, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2009

机译：MCF7乳腺癌细胞中脂质过氧化醛DODE改性蛋白质的鉴定。
5. Modification of proteins by lysine-directed bifunctional aldehydes derived from lipid peroxidation. [D] . Liu, Zhongfa. 2003

机译：赖氨酸定向的双功能醛衍生的脂质过氧化修饰蛋白质。
6. Knock-out of SO1377 gene which encodes the member of a conserved hypothetical bacterial protein family COG2268 results in alteration of iron metabolism increased spontaneous mutation and hydrogen peroxide sensitivity in Shewanella oneidensis MR-1 [O] . Weimin Gao, Yongqing Liu, Carol S Giometti, 2006

机译：SO1377基因的敲除编码一个保守的假设细菌蛋白家族COG2268的成员导致铁代谢代谢改变自发突变增加以及Sheidella oneidensis MR-1中的过氧化氢敏感性
7. Knock-out of gene, which encodes the member of a conserved hypothetical bacterial protein family COG2268, results in alteration of iron metabolism, increased spontaneous mutation and hydrogen peroxide sensitivity in MR-1 [O] . 2006

机译：基因的敲除，编码一个保守的假设细菌蛋白家族COG2268的成员，导致铁代谢的改变，MR-1的自发突变增加和过氧化氢敏感性

Some Problems of Spontaneous Protein Peroxidation

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