Synthesis of 6-Bromo-6-dezoxy-bete-cyclodextrin from Its Silyl and Tosyl Derivatives

摘要

6-Bromo-6-dezoxy derivatives of bete-cyclodextrin attract a permanent interest owing to their high alkylating properties toward N-containing organic nucleophiles because they allow to prepare numerous alkylammonium derivatives of cyclodextrins that significantly extends the possibility of cyclodextrins practical usage,for example for the synthesis of bete-cyclodextrin cationic derivatives.Bromodezoxy derivatives of cyclodextrins are usually prepared by the reaction of spare cyclodextrins with Riden and Wilsmier-Haack reagents.