Synthesis and Ionophoric Properties of alpha,omega-Diphosphorylated Aza Podands:II.Kabachnik-Fields Reaction as a Method for Design of alpha,omega-Diphosphorylated Aza Podands and Their Use for Determination of Metal Ions

摘要

Methods of the design of podands with alpha-aminomethylphosphine oxide terminal groups with the purpose of investigation of the ionophoric properties of the podands and their use as components of ion-selective electrodes are analyzed.The most convenient procedure is a one-pot synthesis based on the Kabachnik-Fields reaction in a system comprising a dialkyl(aryl)phosphinous acid,formaldehyde,and a diamine.An alternative procedure is two-stage and involves the reaction of a primary amine with a phosphinous acid and formaldehyde to form an alpha-aminomethyldialkyl(aryl)phosphine oxide in the first stage and cross-linking of two molecules of this compound via reaction with a dihalooligoether of the corresponding length in the second.Advantages and disadvantages of both procedures are considered.Electrode-active properties of the prepared aza podands are studied to show that ion-selective electrodes on their basis can be used for selective determination of low concentrations of alkali and alkaline-earth metal ions.