Synthesis and Antimicrobial Activity of o- and p-Hydroxybenzoic Acid Thiosemicarbazides

摘要

The ortho- and para-hydroxybenzoic acid thiosemicarbazide derivatives which are potentially biologically active substances were obtained by the reaction of the corresponding hydrazides with various isothiocyanates. Their structures were determined using IR, ~1H NMR spectroscopy, and mass spectrometry. Pronounced antimicrobial activity of synthesized derivatives was revealed.