Vanilline Alkanoates in the Synthesis of Hexahydrobenzacridine and Octahydroxanthene Derivatives

摘要

Cascade heterocyclization of 1,3-cyclohexanedione and dimedone with 2-naphthylamine and vanilline esters gave derivatives of 2-methoxy-4-(alkyl-11-oxo-7,8,9,10,11,12-hexahydrobenz[a]acridin-12-yl)-and 2-methoxy-4-(alkyl-1,8-dioxo-2,3,4,5,6,7,8,9-octahydro-lH-xanthen-9-yl)phenyl esters of aliphatic (C_1-C_4) carboxylic acids.