Synthesis of l-(3-Phenoxyphenyl)butane-1,3-dione from Ethyl Acetoacetate

摘要

1,3-Diketones occupy an important place among various diphenyl oxide derivatives [1]. The presence of two reaction sites in the molecule makes them indispensable synthons for obtaining the new substances possessing a high biological activity. For example, 1,3-chketones can be used for the synthesis of 3-hydroxyketones, pyrazolo[5,l-c]-1,2,4-triazines [2], N-substituted aminopyridones [3], flavones, isoxazoles [4] and also as ligands in metal-polymer compounds [5], in polymer chemistry to improve dispersion of thermostabilizers in the compositions of halogenated polymers [6].