Development Strategies and Biopharmaceutical Aspects of Drug Delivery Systems

摘要

One of the approaches to enhancing drug efficiency consists in the development of drug delivery systems. Development, research, and standardization of biologically available, functional, molecularly structured systems with unique mechanical, physicochemical, and other properties requires joint effort of many disciplines: from materials science to pharmacy. The main goal of the development of drug delivery systems is to prolong residence of a drug in biological fluids (this first of all relates to readily soluble pharmaceutical substances), ensure targeted action (especially with highly toxic substances), and enhance solubility for improving its bioavalability (with sparingly soluble substances).