Synthesis of 2-Amino-4-phenylthiazole-Derived Thiuram Disulfide

摘要

Thiuram disulfides, many of them revealing various utilitarian properties, are among the most important classes of organic sulfur compounds. For instance, tetraethylthiuram disulfide (Teturam, Disulfiram) is used in medicine to treat chronic alcoholism, and tetramcthylthiuram disulfide accelerates rubber cooling and has been intensively applied in the industry [1], Tetramcthylthiuram disulfide is used in preparation of antihypertensive drug clonidine as well. N,N-Bis-(vinyloxyethyl)thiuram disulfide homopolymer obtained by cationic polymerization is a selective adsorbent of mercury and noble metals .