The neuroprotective effect of erythropoietin on spinal motor neurons after nerve root avulsion injury in rats

Noguchi Takashi; Ohta Souichi; Kakinoki Ryosuke; Ikeguchi Ryosuke; Kaizawa Yukitoshi; Oda Hiroki; Matsuda Shuichi

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The neuroprotective effect of erythropoietin on spinal motor neurons after nerve root avulsion injury in rats

机译：促红细胞生成素对大鼠神经根撕脱伤后脊髓运动神经元的神经保护作用

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Purpose: The rapid death of many spinal motor neurons after nerve root avulsion injury results in limited functional recovery following replantation surgery of avulsed nerves into the spinal cord. Therefore, we investigated the neuroprotective effect of erythropoietin (EPO) on motor neurons after nerve root avulsion injury using a rat model.

机译：目的：神经根撕脱伤后许多脊髓运动神经元的快速死亡导致将撕脱神经再植入脊髓后的功能恢复受限。因此，我们使用大鼠模型研究了促红细胞生成素（EPO）对神经根撕脱伤后运动神经元的神经保护作用。

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《Restorative neurology and neuroscience》 |2015年第4期|共10页
作者
Noguchi Takashi; Ohta Souichi; Kakinoki Ryosuke; Ikeguchi Ryosuke; Kaizawa Yukitoshi; Oda Hiroki; Matsuda Shuichi;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Nerve root avulsion injury; oxidative stress; rat; motor neurons; erythropoietin;

机译：神经根撕脱伤;氧化应激;大鼠;运动神经元;促红细胞生成素;

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1. The neuroprotective effect of erythropoietin on spinal motor neurons after nerve root avulsion injury in rats [J] . Noguchi Takashi, Ohta Souichi, Kakinoki Ryosuke, Restorative neurology and neuroscience . 2015,第4期

机译：促红细胞生成素对大鼠神经根撕脱伤后脊髓运动神经元的神经保护作用
2. Expressions of miR-132, miR-134, and miR-485 in rat primary motor cortex during transhemispheric functional reorganization after contralateral seventh cervical spinal nerve root transfer following brachial plexus avulsion injuries [J] . Neuroreport . 2016,第1期

机译：臂丛神经撕脱伤后对侧第七颈脊髓神经根转移后半球功能重组期间大鼠原发性运动皮层中miR-132，miR-134和miR-485的表达
3. Motor nerve graft is better than sensory nerve graft for survival and regeneration of motoneurons after spinal root avulsion in adult rats. [J] . Chu TH, Du Y, Wu W Experimental Neurology . 2008,第2期

机译：在成年大鼠脊髓根部撕脱后运动神经元的存活和再生方面，运动神经移植优于感觉神经移植。
4. The Animal Model on Reimplantation of Nerve Root to the Spinal Cord after Root Avulsion of Brachial Plexus in Rats [C] . Pingguang Xia, Liqiang Gu Third International Conference of China on Anatomical Sciences Sep 21-24, 2001 Nantong, China . 2001

机译：大鼠臂丛神经根撕脱伤后神经根再植入脊髓的动物模型
5. Differentiation and Subtype Specification of Spinal Motor Neurons through a Program of Foxp1, Foxp2, and Foxp4 Gene Expression: Therapeutic Implications for Regenerative Medicine in Spinal Nerve Injury and Disease [D] . Rousso, David Leon 2010

机译：通过程序Foxp1，Foxp2和Foxp4基因表达的脊髓运动神经元的分化和亚型规范：脊髓神经损伤和疾病的再生医学的治疗意义。
6. Long-Term Effects of a Lumbosacral Ventral Root Avulsion Injury on Axotomized Motor Neurons and Avulsed Ventral Roots in a Non-Human Primate Model of Cauda Equina Injury [O] . Marcus Ohlsson, Jaime H. Nieto, Kari L. Christe, -1

机译：腰ac神经根撕脱损伤对非人灵长类马尾神经损伤模型中轴突运动神经元和撕脱的根根的长期影响。
7. The neuroprotective effect of erythropoietin on spinal motor neurons after nerve root avulsion injury in rats. [O] . Noguchi Takashi, Ohta Souichi, Kakinoki Ryosuke, 2015

机译：促红细胞生成素对大鼠神经根撕脱伤后脊髓运动神经元的神经保护作用。

The neuroprotective effect of erythropoietin on spinal motor neurons after nerve root avulsion injury in rats

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