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Radiochromic film for individual patient QA in extracranial stereotactic lung radiotherapy (Conference Paper)

机译:颅外立体定向肺放射治疗中个别患者QA的放射致变色膜(会议论文)

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Modern radiotherapy is characterised by increasingly complex radiation delivery such as Intensity Modulated Radiation Therapy (IMRT) or extracranial stereotactic radiotherapy (ESR). It has become common practice to verify the delivery for each patient in IMRT, however, no such methods have been defined to date for ESR. It was the aim of the present work to develop a method to verify the dose distribution for ESR in a moving phantom using radiochromic film. Methods: Radiochromic film (ISP EBT2) was used in a cylindrical film cassette fitted into a QUASAR phantom (Modus Medical). The cassette can be moved forwards and backwards with motion patterns that can mimic the breathing of individual patients. The radiotherapy treatment plans of four patients were re-planned for the phantom. Between 8 and 10 radiation fields of 6 MV photons from a Varian Trilogy linear accelerator were used to deliver target doses between 18 and 26 Gy per fraction. In order to allow for measurements with EBT2 film all monitor units were divided by 3 or 4 resulting in maximum doses not exceeding 10 Gy. The film was evaluated using a transmission scan on an Epson Perfection V700 scanner with 50 dpi spatial resolution (3 colors, 48bit). A calibration curve was used to convert either the red or green component of the scan to dose. Results: Qualitative film analysis found no discernible discrepancies from planned isodose distributions in the stationary images. The dose distribution in the moving phantom was used successfully to confirm the appropriateness of the ITV construction in the planning process. Conclusions: We have developed a QA procedure that accounts for breathing patterns of individual patients in ESR for lung cancer. Radiochromic film was found to be easy to adapt to this process.
机译:现代放射疗法的特点是放射传递越来越复杂,例如强度调节放射疗法(IMRT)或颅外立体定向放射疗法(ESR)。在IMRT中验证每位患者的分娩已成为一种普遍做法,但是,迄今为止,尚未为ESR定义此类方法。本工作的目的是开发一种方法来验证使用放射致变色胶片的运动体模中ESR的剂量分布。方法:将放射致变色胶片(ISP EBT2)用于安装在QUASAR体模(Modus Medical)中的圆柱形胶片盒中。盒式磁带可以以模仿单个患者呼吸的运动模式来回移动。对四名患者的放射治疗计划进行了重新规划以用于幻影。来自Varian Trilogy线性加速器的6个MV光子在8至10个辐射场之间的目标剂量为每部分18至26 Gy。为了允许使用EBT2胶片进行测量,将所有监控器单元除以3或4,导致最大剂量不超过10 Gy。在具有50 dpi空间分辨率(3色,48位)的Epson Perfection V700扫描仪上使用透射扫描对胶片进行了评估。使用校准曲线将扫描的红色或绿色分量转换为剂量。结果:定性胶卷分析未发现固定图像中计划的等剂量分布有可辨别的差异。运动模型中的剂量分布已成功用于确认ITV结构在规划过程中的适当性。结论:我们已经开发了一种QA程序,该程序可以解释ESR患肺癌的个体患者的呼吸模式。发现辐射致变色膜易于适应该过程。

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