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EPR of gamma-irradiated polycrystalline alanine-in-glass dosimeter

机译:γ辐照多晶丙氨酸玻璃剂量计的EPR

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This study attempts to overcome some of the reported discrepancies in alanine-EPR reproducibility that may be related to alanine dosimeter preparation and/or EPR spectrometer settings. The dosimeters were prepared by packing pure polycrystalline L-α-alanine directly as supplied by the manufacturer in glass tubes. This dosimeter production scheme avoids any possible contribution to the EPR signal from a binding material. The dosimeters were irradiated with gamma ray to low-dose ranges typical for medical therapy (0–20 Gy). Special attention has been paid to the study of minimum detectable dose, measurement repeatability and reproducibility, and post-irradiation stability. The dosimeter exhibited a linear dose response in the dose range from 0.1 to 20 Gy. These positive properties favor the polycrystalline alanine-in-glass tube as a radiation dosimeter.
机译:这项研究试图克服某些报道的丙氨酸-EPR重现性差异,这些差异可能与丙氨酸剂量计的制备和/或EPR光谱仪设置有关。通过将制造商提供的纯多晶L-α-丙氨酸直接包装在玻璃管中来制备剂量计。这种剂量计生产方案避免了来自结合材料的EPR信号的任何可能贡献。剂量计用伽马射线辐照到药物治疗中通常的低剂量范围(0-20 Gy)。特别注意最小可检测剂量,测量重复性和再现性以及辐照后稳定性的研究。剂量计在0.1至20 Gy的剂量范围内表现出线性剂量响应。这些积极特性有利于将多晶玻璃丙氨酸管用作辐射剂量计。

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