DIFFUSE MACULAR EDEMA IN NIACIN-INDUCED MACULOPATHY MAY RESOLVE WITH DOSAGE DECREASE

摘要

Purpose: To report on a patient with niacin-induced cystic maculopathy that resolved with dosage decrease, not discontinuation, of niacin therapy for dyslipidemia.Methods: Retrospective case report. The patient was being followed for vision changes, but his niacin therapy was managed elsewhere.Results: Results of the decrease in niacin dosage show clear evidence (with optical coherence tomography) of resolution of retinal edema.Conclusion: The authors conclusion is that niacin's toxicity has a threshold, and dosage decrease below this threshold allows continuation of therapy at the lower dosage without clinically evident adverse effects on the retina.