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Noninvasive CPAP with face mask: Comparison among new air-entrainment masks and the boussignac valve

机译:带有面罩的无创CPAP:新式空气夹带面罩和boussignac瓣膜之间的比较

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BACKGROUND: The performances of 2 noninvasive CPAP systems (high flow and low flow air-entrainment masks) were compared to the Boussignac valve in 3 different scenarios. METHODS: Scenario 1: pneumatic lung simulator with a tachypnea pattern (tidal volume 800 mL at 40 breaths/ min). Scenario 2: Ten healthy subjects studied during tidal breaths and tachypnea. Scenario 3: Twenty ICU subjects enrolled for a noninvasive CPAP session. Differences between set and effective CPAP level and FIO2, as well as the lowest airway pressure and the pressure swing around the imposed CPAP level, were analyzed. The lowest airway pressure and swing were correlated to the pressure-time product (area of the airway pressure curve below the CPAP level) measured with the simulator. PaO2 was a subject's further performance index. RESULTS: Lung simulator: Boussignac FIO2 was 0.54, even if supplied with pure oxygen. The air-entrainment masks had higher swing than the Boussignac (P = .007). Pressure-time product correlated better with pressure swing (Spearman correlation coefficient [ρ] = 0.97) than with lowest airway pressure (ρ = 0.92). In healthy subjects, the high-flow air-entrainment mask showed lower difference between set and effective FIO2 (P.001), and lowest airway pressure (P .001), compared to the Boussignac valve. In all measurements the Boussignac valve showed higher than imposed CPAP level (P .001). In ICU subjects the high-flow mask had lower swing than the Boussignac valve (P = .03) with similar PaO2 increase. CONCLUSIONS: High-flow air-entrainment mask showed the best performance in human subjects. During high flow demand, the Boussignac valve delivered lower than expected FIO2 and showed higher dynamic hyper-pressurization than the air-entrainment masks.
机译:背景:在3种不同的情况下,将2种无创CPAP系统(高流量和低流量加气口罩)的性能与Boussignac瓣膜进行了比较。方法:场景1:具有呼吸暂停模式的肺部模拟器(潮气量800 mL,每分钟40次呼吸)。方案2:在潮气和呼吸急促中研究了十名健康受试者。方案3:招募了20名ICU受试者参加无创CPAP会话。分析了设定的和有效的CPAP水平与FIO2之间的差异,以及最低的气道压力和所施加的CPAP水平附近的压力摆幅。最低气道压力和摆动与使用模拟器测量的压力时间乘积(气道压力曲线的面积低于CPAP水平)相关。 PaO2是受试者的进一步表现指标。结果:肺模拟器:即使提供纯氧,Boussignac FIO2也为0.54。防空气罩的摆动比Boussignac高(P = .007)。压力时间乘积与压力摆幅(Spearman相关系数[ρ] = 0.97)的相关性比与最低气道压力(ρ= 0.92)的相关性更好。在健康受试者中,与Boussignac瓣膜相比,高流量导气面罩显示设定FIO2与有效FIO2之间的差异较小(P <.001),而最低呼吸道压力(P <.001)。在所有测量中,Boussignac瓣膜均显示出高于所施加的CPAP水平(P <.001)。在ICU受试者中,高流量面罩的摆动比Boussignac瓣膜的摆动低(P = .03),且PaO2升高相似。结论:高流量引气面罩在人类受试者中表现出最好的表现。在高流量需求期间,Boussignac阀的送气量低于预期的FIO2,并且比空气夹带面罩显示出更高的动态超压。

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