CHOROIDAL NEOVASCULARIZATION COMPLICATING PHOTODYNAMIC THERAPY FOR CENTRAL SEROUS RETINOPATHY

摘要

Central serous retinopathy (CSR) is characterized by localized serous retinal detachment in the macular region due to a breakdown in the outer blood-retinal barrier (at the retinal pigment epithelium [RPE]). Patients with CSR present with visual blurring, distortion, micropsia, and a positive scotoma in the central field of vision. Most cases of CSR are self-limited, with a duration of 6 weeks to 8 weeks. However, recurrences are frequent, occurring in about one third of all patients after the first episode of the disease. Chronic and recurrent CSR can be visually disabling in these patients. Macular RPE atrophy with associated atrophic photoreceptor degeneration and (in a few cases) choroidal neovascularization (CNV) may accompany chronic and recurrent CSR.