Surgical drainage of a pigment epithelial detachment in neovascular age-related macular degeneration.

摘要

Retinal pigment epithelium detachments (PEDs) due to neovascular age-related macular degeneration (AMD) occur commonly and spontaneous resolution is rare. PEDs usually result in atrophy, but may also result in retinal pigment epithelium (RPE) tears, hemorrhage, and scarring when associated with cho-roidal neovascularization. Currently, no well-defined approach for managing PEDs in neovascular AMD exists. Antivascular endo-thelial growth factor (VEGF) agents alone or in combination with photodynamic therapy have been used to improve vision in these patients. Anti-VEGF agents frequently resolve associated retinal and subretinal edema but often do not reduce the size of PEDs.3 In addition, RPE tears have occurred in patients with PEDs due to neovascular AMD treated with anti-VEGF agents, often resulting in severe vision loss. We report a successful outcome of surgically draining a PED in a patient with neovascular AMD who had progressive vision loss despite treatment with intrav-itreal ranibizumab.