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Grid laser treatment for exudative retinal detachment secondary to ischemic branch retinal vein occlusion.

机译:网格激光治疗继发于缺血性分支视网膜静脉阻塞的渗出性视网膜脱离。

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PURPOSE:: To evaluate the effectiveness of macular grid laser photocoagulation (MGLP) in obtaining the reabsorption of exudative retinal detachment (ERD) in patients with ischemic branch retinal vein occlusion (BRVO). METHODS:: Prospective, randomized clinical trial including 31 patients with ERD secondary to ischemic BRVO, who were randomized either to MGLP or to observation. A complete ophthalmologic examination was performed within 7 days of treatment, and was arranged to be repeated regularly every 6 months for 24 months. MGLP was performed using a krypton laser with a spot size of 100 mum at 0.1 second. The main outcome measure was the number of eyes that had gained at least 15 letters at the 24-month examination in the two groups. RESULTS:: By the month 24 visit, 40% of the patients in the MGLP group had gained at least three lines of visual acuity as opposed to no patient in the control group. The mean best-corrected visual acuity passed from 20/160 to 20/125 Snellen equivalent in the MGLP group, and from 20/160 to 20/400 Snellen equivalent in the control group at month 24. The difference in the mean reabsorption time was statistically significant (P < 0.001) comparing the treated group with the controls (9.1 versus 15.8 months). CONCLUSION:: Natural history of ERD secondary to ischemic BRVO is poor, and MGLP is able to prevent visual acuity deterioration through a 24-month follow-up.
机译:目的:评价黄斑栅格激光光凝(MGLP)在缺血性视网膜分支静脉阻塞(BRVO)患者中获得渗出性视网膜脱离(ERD)的重吸收的有效性。方法:一项前瞻性随机临床试验,包括31例继发于缺血性BRVO的ERD患者,他们被随机分配至MGLP或观察。在治疗的7天内进行了完整的眼科检查,并安排为每6个月定期重复进行24个月。 MGLP用using激光在0.1秒处进行,光斑大小为100微米。主要结局指标是两组在24个月检查中至少获得15个字母的眼睛数。结果:到第24个月就诊时,MGLP组中40%的患者至少获得了三行视敏度,而对照组中没有患者。 MGLP组的平均最佳矫正视力在第24个月从20/160 Snellen当量,对照组在20/160 Snellen当量至20/400 Snellen当量。平均重吸收时间的差异为比较治疗组和对照组(9.1个月与15.8个月),具有统计学意义(P <0.001)。结论:继发于缺血性BRVO的ERD的自然病程较差,并且MGLP能够通过24个月的随访来预防视力下降。

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