PURPOSE: A system to produce three-dimensional computer reconstructions of ophthalmic contact B-scan ultrasound was developed and investigated. METHODS: Investigators used ocular phantoms to measure the accuracy and reproducibility of linear, area, and volume measurements. RESULTS: In vitro calibration tests of linear and area measurements demonstrate accurate and reproducible findings throughout the imaged space. Phantom volume tests also show reasonable accuracy and reproducibility. CONCLUSIONS: Three-dimensional ultrasonography is effective in measuring length, area, and volume in an experimental model. The in vitro accuracy and reproducibility of measurements warrants further investigation into the clinical utility of this method in posterior segment tumors and other posterior segment pathology.
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