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首页> 外文期刊>Retina >Internal limiting membrane peeling for decompression of macular edema in retinal vein occlusion: a report of 14 cases.
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Internal limiting membrane peeling for decompression of macular edema in retinal vein occlusion: a report of 14 cases.

机译:内限膜剥离治疗视网膜静脉阻塞性黄斑水肿减压:附14例报道。

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BACKGROUND: Currently, there is no proven treatment for macular edema due to central retinal vein occlusion (CRVO). Moreover, not all cases with macular edema due to branch retinal vein occlusion (BRVO) respond to laser photocoagulation. We postulated that internal limiting membrane (ILM) peeling for decompression of macular edema in cases of retinal vein occlusion would facilitate egress of blood and extracellular fluid out of the inner retinal layers, leading to reduction of macular edema and improvement in visual acuity. METHODS: Fourteen consecutive patients with macular edema due to CRVO or selected cases of BRVO, not eligible for laser photocoagulation, underwent pars plana vitrectomy with removal of preretinal hyaloid and peeling of the ILM stained with indocyanine green dye. RESULTS: In all cases, intraretinal blood and retinal thickening diminished within 6 weeks of surgery. Visual acuity improved in 78.6% of cases. No surgical complications occurred, although one patient developed nuclear cataract 10 months postoperatively. CONCLUSION: Pars plana vitrectomy with ILM peeling in selected cases of CRVO and BRVO showed improvement in visual acuity in this nonrandomized, noncontrolled study. This pilot study adds support to the concept that ILM peeling may of visual benefit when compared with the natural history in these vaso-occlusive diseases.
机译:背景:目前,由于视网膜中央静脉阻塞(CRVO),尚无行之有效的黄斑水肿治疗方法。此外,并非所有因视网膜分支静脉阻塞(BRVO)而引起的黄斑水肿的病例都对激光光凝反应有反应。我们假设在视网膜静脉闭塞的情况下使用内部限制膜(ILM)剥离来减轻黄斑水肿会促进血液和细胞外液从视网膜内层流出,从而减少黄斑水肿并改善视力。方法:连续14例因CRVO引起的黄斑水肿或某些不适合进行激光光凝治疗的BRVO病例,行平面玻璃体切除术,去除视网膜前的透明样体,并用吲哚花青绿染料将ILM剥离。结果:在所有情况下,手术后6周内视网膜内血液和视网膜增厚均减少。 78.6%的患者的视力得到改善。尽管一名患者术后10个月出现了核性白内障,但没有发生手术并发症。结论:在这项非随机,非对照研究中,在部分CRVO和BRVO病例中,伴有ILM剥脱的Pars平板玻璃体切除术显示了视力的改善。这项初步研究为以下观点提供了支持:与这些血管闭塞性疾病的自然史相比,ILM剥离可能具有视觉益处。

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