Twin pregnancy in a 51-year-old woman who underwent autologous cryopreservation at the age of 36 years: case report

摘要

Climacteric women are able to become pregnant using oocytes donated earlier in life. However, adverse effects on such donated oocytes have been identified. We report a case of a successful dichorionic diamniotic twin pregnancy achieved using autologous fertilized cryopre-served oocytes in a climacteric woman. A 51-year-old woman became pregnant using autologous fertilized oocytes that had been frozen for 15 years. On her first visit, multiple leiomyoma of the uterus and gestational diabetes mellitus were diagnosed, and proteinuria began to appear at 30 weeks. In spite of our concerns these complications did not exacerbate and the clinical course for both mother and neonates was favorable. This is the first report of a live twin birth achieved using autologous cryopreserved oocytes in a climacteric woman. This case report may be of value to women who desire postponement of their infertility treatment and the professional assisted reproduction community.