首页> 外文期刊>Regulatory peptides. >Vascular effects of oxytocin on human middle cerebral artery determined by transcranial Doppler sonography.
【24h】

Vascular effects of oxytocin on human middle cerebral artery determined by transcranial Doppler sonography.

机译:经颅多普勒超声确定催产素对人大脑中动脉的血管作用。

获取原文
获取原文并翻译 | 示例
           

摘要

Neurohypophysial hormones may exert regulatory influences on cerebral blood flow. This double-blind cross-over study in healthy humans (n = 6) examined effects of oxytocin (OX) on blood flow in the middle cerebral artery (MCA) by transcranial Doppler sonography. Compared to placebo, intravenous infusion of OX (0.5 IU, within 2.5 min via a forearm catheter) reduced blood flow velocity (V) within 10 min after the start of the infusion (P < 0.05). The pulsatility index (PI) was at the same time increased following OX (P < 0.05). The effects of OX were not accompanied by changes in expiratory endtidal pCO2 or blood pressure. But, heart rate was slightly enhanced immediately after infusion of OX (P < 0.05). The changes in MCA blood flow velocity following OX could reflect a vasoconstrictory effect on small cerebral resistance vessels or a vasodilating effect on the large cerebral arteries.
机译:神经垂体激素可能对脑血流产生调节作用。这项针对健康人(n = 6)的双盲交叉研究通过经颅多普勒超声检查了催产素(OX)对大脑中动脉(MCA)血流的影响。与安慰剂相比,OX的静脉输注(0.5 IU,通过前臂导管在2.5分钟内)在输注开始后10分钟内降低了血流速度(V)(P <0.05)。 OX后,搏动指数(PI)同时增加(P <0.05)。 OX的影响未伴有呼气末期pCO2或血压的变化。但是,立即注入OX后,心率略有提高(P <0.05)。 OX后MCA血流速度的变化可能反映了对小脑阻力血管的血管收缩作用或对大脑动脉的血管舒张作用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号