Biochemical Assessment of the Effects of Soap and Detergent Industrial Effluents on Some Enzymes in the Stomach of Albino Rats.

摘要

The effects of soap and detergent industrial effluents on some enzymes in the stomach of Albino rats (Rattus norvegicus) were investigated. Four concentrations (5, 25, 50 and 10G% v/v) of the effluent were used as the main sources of water for four groups of rats over thirty days while feeding the rats ad libitum with a commercial rat chow such that the method of feeding did not constitute a variable. Tap water was used as the control water. The physicochemical characteristics of the effluents and tap water were determined and compared with WHO standard. The average life weight gain was measured at every fifth days. At the end of the experiment, the rats were sacrificed and activities of alanine amino transferase (ALT), aspartate amino transferase (AST), lactate dehydrogenase (LDH) and alkaline phosphatase (ALP) were monitored in the stomach of the rats as a means of assessing the biochemical implication of the consumption of the chemical effluents. Soap and detergent industrial effluents presentedhigh level of Biochemical Oxygen Demand (BOD), chemical oxygen demand (COD), Total Dissolved Solids (TDS) and some heavy metals like Pb, Cd and Mn. There were significant (p<0.05) difference and effluent concentration dependent increase in the activityof ALT, AST, LDH while ALP activity showed an effluent concentration dependent decrease in the stomach of the rats. The results showed that the consumption of the water contaminated with soap and detergent industrial effluents may be involved in the stomach dysfunction.